Abstract
Focusing on the intestine, the liver and the lung, the aim of this project is to develop techniques to engineer the cells of the vasculature and to define the conditions necessary for their growth and development. Specifically, the principal deliverable will be to engineer organs with a fully restored and functional vascular bed.
The students will deal with the decellularisation of tissues and organs and with the culture of endothelial and perivascular cells derived from pluripotent and aminiotic fluid stem cells. Furthermore the student will design a bioreactor to deliver the culture for the re-endothelialisation of decellularised organs.
References
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