Novel cryogen free sensors for high resolution laminar-specific magnetoencephalography    

Sven Bestmann (primary)
Sobell Department for Motor Neuroscience and Movement Disorders
University College London
Gareth Barnes (secondary)
Wellcome Centre for Human Neuroimaging
University College London

Abstract

Novel wearable, cryogen-free, optically-pumped magnetometers (OPMs) for MEG promise vast improvements in signal-to-noise recordings of brain activity in humans. In simulations we have shown that this may allow for non-invasive electrophysiological recording of brain activity at unprecedented resolution. Moreover, OPMs in principle allows for unconstrained recordings of brain activity in healthy individuals and patients.  We now have installed the first system of its kind, and this project will develop methods and strategies for using OPMs in health and patient populations, with the potential to overcome the limitations of conventional MEG and revolutionize human neuroimaging.


References

  1. Troebinger et al Neuroimage 2014a 102:885-893
  2. Troebinger et al Neuroimage 2014 86:583-591
  3. Klein-Flugge M, et al PLoS Comp Biol 11(3):e1004116.
  4. Meyer et al, NeuroImage 2017 149:468-82
  5. Boto et al Neuroimage 2017 149: 404-414

BBSRC Area
Molecules, cells and industrial biotechnology
Area of Biology
BiotechnologyNeurobiology
Techniques & Approaches
EngineeringGeneticsImage ProcessingMathematics / StatisticsMicroscopy / ElectrophysiologySimulation / Modelling