3D modelling and haemodynamic analysis of patient specific abdominal aortic aneurysms

Richard Bomphrey (primary)
Comparative Biomedical Sciences
Royal Veterinary College
Yiannis Ventikos (secondary)
Mechanical Engineering
UCL

Abstract

In an age of increased demand for cardiovascular interventions – surgical but also minimally invasive – there is an urgent need for improved and reliable prognostics in patients presenting with abdominal aortic aneurysms. Is it possible to inform predictions of rupture risk using biomedical imaging data direct from the clinic? This work builds on pre-existing simplified computational models that couple the fluid dynamics of blood with the structural dynamics of aortic tissue.


References

Implementing fluid-structure interaction computational and empirical techniques to assess hemodynamics of abdominal aortic aneurysms.
H Safi, N Phillips, Y Ventikos, R Bomphrey
Artery Research
(2017)

Thrombosis in Cerebral Aneurysms and the Computational Modeling Thereof: A Review
MN Ngoepe, AF Frangi, JV Byrne, Y Ventikos
Frontiers in Physiology
(2018)

Investigating cerebral oedema using poroelasticity
JC Vardakis, D Chou, B Tully, CC Hung, TH Lee, P-H Tsui, Y Ventikos
Medical Engineering & Physics
(2015)

Investigating cerebral oedema using poroelasticity
Smart wing rotation and trailing-edge vortices enable high frequency mosquito flight
RJ Bomphrey, T Nakata, N Phillips, SM Walker
Nature
(2017)


BBSRC Area
Animal disease, health and welfare
Area of Biology
BiotechnologyPhysiology
Techniques & Approaches
BiophysicsEngineeringImage ProcessingSimulation / Modelling