A 3D Stem Cell Bandage For Bone Repair

Shukry James Habib (primary)
Stem Cells and Regenerative Medicine (CSCRM)
King's College London
Alvaro Mata (secondary)
Biomedical Engineering and Biomaterials
Queen Mary, University of London

Abstract

Large bone fractures represent a major cause of disabilities and morbidity globally and result in enormous costs for health and social care systems. Stem cell-based tissue engineering holds a great promise for improving human health by using stem cells to repair damaged tissues in the body or replace diseased tissue with a healthy tissue. The proposed project will combine the expertise in stem cell biology (Habib Lab) and advanced biomaterial design (Mata lab) to generate a living 3D human osteogenic tissue in vitro, characterise its function and probe its potential to repair severe bone defect of murine Calvaria.


References

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BBSRC Area
Animal disease, health and welfare
Area of Biology
BiotechnologyCell Biology
Techniques & Approaches
BiochemistryBiophysicsChemistryEngineeringGeneticsImage ProcessingMathematics / StatisticsMicroscopy / ElectrophysiologyMolecular BiologySimulation / Modelling