Abstract
Large bone fractures represent a major cause of disabilities and morbidity globally and result in enormous costs for health and social care systems. Stem cell-based tissue engineering holds a great promise for improving human health by using stem cells to repair damaged tissues in the body or replace diseased tissue with a healthy tissue. The proposed project will combine the expertise in stem cell biology (Habib Lab) and advanced biomaterial design (Mata lab) to generate a living 3D human osteogenic tissue in vitro, characterise its function and probe its potential to repair severe bone defect of murine Calvaria.
References
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