Abstract
Alleviating pain following bone fracture in both animals and humans is essential to allow the patient to participate in the physical rehabilitation necessary for full recovery. However, pain management after bone fracture is problematic and presents a growing problem, particularly among older individuals. This is because the mechanisms leading to bone pain after fracture are still not well understood. In this project, the PhD student will use a multidisciplinary approach to elucidate, in animals, the spinal mechanisms that maintain persistent pain after bone fracture using a range of behavioural, molecular and analytical approaches.
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