A sustainable and environmentally friendly approach combining DNA-catalysis and photocatalysis for the manufacturing of sulfoxide privileged scaffolds will be developed. Chiral sulfoxides are widely spread molecules in nature and can be found in many foods and plants. They have important dietary and therapeutic roles and are known to be potent antibacterial agents. The synthesis of sulfoxides in enantiomerically pure form still represents a challenge in chemistry. This project will investigate the use of green catalytic technologies such as DNA-catalysis and photo-biocatalysis, to allow the synthesis of chiral sulfoxide derivatives in a sustainable and environment friendly way.
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