Abstract
With a growing resistance developing to current antimicrobial compounds there is a need to expand the armoury of those used to include novel naturally occurring compounds, especially if these can act as templates for developing more potent synthesised pharmaceuticals. One area for investigation is peptides that naturally punch holes in microbial membranes. This project will characterise these natural materials and their interactions with these membranes with a view to developing peptides from them for applications in the health and agricultural areas. Computational tools developed and utilised for these data analyses will also see use in the wider scientific community.
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