Abstract
Fungally-infected nails are colonised by a complex microbial community, rather than an individual causative fungus. We therefore hypothesise that medicines should be prepared and their efficacies tested against such microbial communities (rather than against one fungus). In this project, the student will examine onychomycotic nails to identify the most common types of microbial communities. They will then develop assays which will enable the measurement of anti-microbial susceptibility of individual, as well as communities, of micro-organisms. Finally, the student will prepare medicine formulations using mixtures of appropriate anti-microbial agents and assess their efficacies against onychomycotic nails.
References
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