Evolutionary rewiring of cellular energy metabolism

Snezhana Oliferenko (primary)
Randall Division of Cell and Molecular Biophysics
King's College London
Jürg Bähler (secondary)
Research Department of Genetics, Evolution & Environment
University College London

Abstract

Energy metabolism is fundamental to all life. We want to understand how the regulation of energy metabolism evolves, and how it can be rewired to produce novel behaviors. This goal will be achieved by integrating bioinformatics, metabolomics and synthetic cell biology approaches in two related yeast species with different physiologies. Our work will provide critical insights into principles underlying metabolic changes associated with human aging and disease.


References

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BBSRC Area
Molecules, cells and industrial biotechnology
Area of Biology
AgeingBiotechnologyCell BiologyEvolutionGeneticsMicrobiologyPhysiology
Techniques & Approaches
BiochemistryBioinformaticsBiophysicsEngineeringGeneticsImage ProcessingMathematics / StatisticsMicroscopy / ElectrophysiologyMolecular Biology