Habituation is a pervasive form of learning that acts as a gateway to cognition, reducing response to inconsequential elements of the environment. Failure of habituation drastically impedes selective attention to meaningful stimuli and events, which is frequently observed in neurodevelopmental psychiatric disorders. Surprisingly, for such a fundamental process, which is equally important to humans and mice, there has not been sufficient research conducted into underlying mechanisms. In this project, the PhD student will gain fundamental insight in mice into basic processes of auditory habituation and how dysfunction may act as an origin for cognitive deficits in psychiatric disorders.
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