Identification and metabolomic characterization of antimicrobial polyphenols from berry fruits

Dr Daniele Castagnolo (primary)
School of Cancer and Pharmaceutical Sciences
King's College London
Dr Ana Rodriguez-Mateos (secondary)
Division of Diabetes and Nutritional Sciences Faculty of Life Sciences and Medicine
King's College London

Abstract

Berry fruits, widely known for their high nutrient and low calorie content, are rich sources of bioactive compounds called polyphenols. These compounds have been widely associated with various therapeutic effects, including antimicrobial activities against a number of human pathogens. This project aims to identify, isolate and characterise the antibacterial polyphenolic compounds from berry extracts and to investigate their metabolic profile and mode of action through the combination of spectroscopic, chemistry and microbiology techniques.


References

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BBSRC Area
Molecules, cells and industrial biotechnologyPlants, microbes, food and sustainability
Area of Biology
Chemical BiologyMicrobiology
Techniques & Approaches
BiophysicsChemistryMolecular Biology