Abstract
Blood oxygenation is a critical measure of physiological function. However, there are very few techniques to reliably measure oxygenation non-invasively. In this interdisciplinary studentship, the student will undertake experimental imaging studies and computational modelling to develop a method to measure oxygenation using a novel technique called photoacoustic tomography. The technique will be tested in phantoms and the kidney, which has different regional areas of oxygenation related to its biological function and in models of hypoxia induced by chemical insults. If successful, this technique would revolutionise preclinical imaging techniques and could be applied to multiple physiological processes and pathological conditions.
References
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