This PhD project aims to identify plasma metabolite markers of accelerated phenotypic ageing in a rural Indian population experiencing social transition. The successful candidate will work with an interdisciplinary supervisory team of clinical epidemiologist and analytical chemist to establish ageing phenotypes in this population, identify known and novel metabolites, and perform data driven and systems/pathway analyses of dysregulated metabolites in the ageing process. The data source for this project will be APCAPS (apcaps.lshtm.ac.uk), an ongoing longitudinal, population-based study of ~6000 adults living in rural and peri-urban Telangana, South India.
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