Neural basis of audiovisual integration during navigation

Kenneth Harris (primary)
UCL Institute of Neurology
University College London
Matteo Carandini (secondary)
UCL Institute of Ophthalmology
University College London


Spatial audiovisual integration is a critical ability, whether prey, predator, or pedestrian crossing the street. However, immersive audiovisual environments remain unstudied, at least in part because colocalizing visual and auditory stimuli throughout space is technologically challenging. We have developed the first audiovisual dome, where visual and auditory stimuli can be colocalized throughout space while head-fixed mice navigate an audiovisual environment. While mice navigate, we propose to record activity in key brain regions with chronically implanted Neuropixels 2.0 probes and determine how auditory and visual navigation signals are combined in the brain.


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Animal disease, health and welfare
Area of Biology
Techniques & Approaches
Microscopy / ElectrophysiologySimulation / Modelling