Novel computational approaches to investigate agonistic and antagonistic interactions in brain functional networks in health and disease

Dr Sagnik Bhattacharyya (primary)
Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience
King's College London
Dr Ginestra Bianconi (secondary)
School of Mathematical Sciences
Queen Mary University of London

Abstract

Interactions between different brain regions may be considered as being broadly of two types, cooperative or agonistic and competitive or antagonistic. Although these opposing types of interactions have been observed in many complex networks, the antagonistic interactions have often not been considered while characterizing human brain networks, giving an incomplete picture of how the brain functions as a whole. This studentship will use human functional neuroimaging data and novel computational approaches (structural balance theory and multilayer networks) to characterize the organization of functional brain networks in health, estimate whether they are heritable and are altered in diseases such as psychosis.


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BBSRC Area
Genes, development and STEM* approaches to biology
Area of Biology
Neurobiology
Techniques & Approaches
Image ProcessingMathematics / Statistics