In recent years, cell delivery using biomaterials has been used to grow new blood vessels and promote regeneration. In a previous study, we found that the administration of biomaterials alone attracted macrophages and enhanced vascularisation of ischaemic tissue. In this project, we propose to investigate the role of macrophages and their behaviour/polarisation in response to their interaction with different types of TIPS biomaterials with the overarching aim of promoting angiogenesis and regeneration.
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