Abstract
Synthetic cannabinoids (SCs) constitute one of the most rapidly expanding class of new psychoactive substances. The metabolism of SCs is also relevant in clinical and forensic toxicology as SCs are excreted in urine mostly as their metabolites. Thus, SC metabolites are widely used as markers for identifying SC intake. There is urgent need for large scale production of SCs metabolites, with subsequent accurate structural identification to enable discovery of new and unidentified metabolites. This project aims at addressing this unmet research need via engineered biocatalytic assays coupled to sophisticated analytical methods for metabolite identification
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