Abstract
The project aim is to develop a stochastic model for avian influenza virus (AIV) transmission in poultry that quantifies the effect of host genetic resistance upon viral dynamics. Influenza dynamics will also be studied in vitro in cell populations that differ in influenza resistance, and mathematical modelling used to quantify how alterations in virus dynamics at the cell level might scale at the population level of the poultry house.
This work addresses what profile of AIV resistance might be needed in commercial poultry populations in order to reduce impact of AIV, a significant threat to food security and public health.
References
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- Fournié , Guitian et al. 2013 Interventions for avian influenza A (H5N1) risk management in live bird market networks. Proc Natl Acad Sci U S A May 28;110(22):9177-82