The genetic adaptations of modern humans to their local environments.

Aida Andres (primary)
Genetics, Evolution and Environment
UCL
Garrett Hellenthal (secondary)
Genetics, Evolution and Environment
GEE

Abstract

Modern humans lived in Africa for millions of years, colonising the rest of the world in the last 50,000-100,000 years. Each new environment differed in ecological factors as important as climate, diet or pathogens, and their colonisation was accompanied by strong pressure to adapt. The resulting genetic adaptations live today as genetic differences among populations, and contribute critically to the phenotypic diversity found in humans today. This project aims to combine modern and ancient genomes to quantify the influence of local adaptation in population differentiation, to identify the loci mediating these adaptations, and to determine their influence in phenotypic diversity.


References

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BBSRC Area
Genes, development and STEM* approaches to biology
Area of Biology
EvolutionGenetics
Techniques & Approaches
BioinformaticsGeneticsMathematics / StatisticsSimulation / Modelling