The role of inflammation in regulating cellular metabolism

Katiuscia Bianchi (primary)
Centre for Molecular Oncology, Barts Cancer Institute
Queen Mary University
Gyorgy Szabadkai (secondary)
Department of Cell and Developmental Biology
University College London


Metabolism is essential to sustain a wide range of fundamental cellular functions. However, it is largely unknown how the extracellular environment contributes to the regulation of cellular metabolism. The PhD project will investigate the hypothesis that a pathway links obesity-related inflammation to cellular metabolism in parenchymal cells in breast secretory cells. We will test this pathway by applying metabolomics, molecular biology, imaging and computational approaches in cellular models and by analysing existing gene expression and metabolomic data in obesity and inflammation driven alterations in breast tissue.


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Molecules, cells and industrial biotechnology
Area of Biology
Cell BiologyChemical Biology
Techniques & Approaches
BiochemistryBioinformaticsImage ProcessingMathematics / Statistics