Abstract
Gene therapy is revolutionising the way we treat lethal genetic diseases. Two FDA approved gene therapies are already on the market that cure genetic diseases from a single injection of viral vectors that deliver a healthy version of a defective gene to cells of the body. However, some diseases are more challenging and require better viral vectors with higher cell tropism. In this project we will use a multidisciplinary approach involving computational techniques, artificial intelligence, cell and molecular biology and animal studies to design the next generation of novel viral vectors and test these in animals.
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