Using Artificial Intelligence to Design the Next Generation of Viral Vectors for Lifesaving Gene Therapy

Prof Ahad Rahim (primary)
UCL School of Pharmacy
University College London
Dr Stephen Goldrick (secondary)
Biochemical Engineering
University College London


Gene therapy is revolutionising the way we treat lethal genetic diseases. Two FDA approved gene therapies are already on the market that cure genetic diseases from a single injection of viral vectors that deliver a healthy version of a defective gene to cells of the body. However, some diseases are more challenging and require better viral vectors with higher cell tropism. In this project we will use a multidisciplinary approach involving computational techniques, artificial intelligence, cell and molecular biology and animal studies to design the next generation of novel viral vectors and test these in animals.


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Molecules, cells and industrial biotechnology
Area of Biology
Techniques & Approaches
BioinformaticsEngineeringMathematics / StatisticsMolecular BiologySimulation / Modelling